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Antiarrhythmic drugs do not lend themselves to a neat classification scheme. Many of these drugs have effects on multiple ion channels and adrenergic receptors as well as a myriad of cardiac and noncardiovascular side effects. The majority of available antiarrhythmic drugs exert predominant effects on cardiac sodium or potassium currents. Accordingly, antiarrhythmic drug therapy primarily includes beta-blockers and class I antiarrhythmic drugs.[43][44] In addition, digoxin is Other information. Drugs may have multiple classes of action e.g. amiodarone shares all four classes of action; Certain agents do not fit this by MC Hyman 2024 Cited by 83Class III antiarrhythmic drugs (AADs), including amiodarone, sotalol, and dofetilide, can be effective, but their use may be limited by organ toxicities antiarrhythmic drug is considered to have a class I indication. Letter from Question: Which Antiarrhythmic Drugs Carry a Class I Recommendation for bupreplast by RJ Hill 2024 Cited by 45To address drug binding to activated and nonactivated states, we exploited the state-specific binding of [3H]BTXB. Drugs that increase the rate by M Singh 2024Class I and III Antiarrhythmic Drugs for Maintaining Sinus Rhythm After Catheter Ablation of Atrial Fibrillation. American family physician, 108
Antiarrhythmic Drugs (Classes I and III) Define antiarrhythmic agents, classifying them by their major impact on specific ion conductance and Are there any differences in outcomes in patients with atrial fibrillation (AF) treated with a class IC drug (flecainide or propafenone) versus Classes of antiarrhythmic drugs are introduced and specific examples are explained regarding their mechanisms and effects on the action potential and use in Quinidine, disopyramide, procainamide, lidocaine, mexiletine, flecainide, and propafenone are all class I antiarrhythmic drugs (table 1) used for the treatment